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Biotech skincare that you can see in the mirror

NX35™ exosome serums for jawline, hair, body and face. Made by two PhD scientists.

  • 4.7 / 5 from 817 reviews
  • 35,000+ happy customers
  • 14 awards incl. Oprah, InStyle & Esquire
  • Free shipping on orders over $75

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One serum per concern: jawline, hair, body and face. Subscribe on any serum and save 15%.

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Awards

    4.7 out of 5 from 577 reviews

    Meet ShapeShift, our #1 bestseller

    The award-winning gel-serum for the jawline and neck, powered by NX35™ exosome technology. One minute, morning and night, for a visibly lifted look in about 4 weeks.

    • Shop TODAY Mature Beauty Awards 2025
    • Cosmopolitan Holy Grail Beauty Awards 2025
    • Best Jawline & Neck Treatment, Real Simple Awards 2024
    • Visibly lifts the jawline and under-chin area
    • Firms and smooths crepey neck skin
    • Vegan, fragrance-free and dye-free
    Choose your set
    How do you want it?
    • Free shipping on every delivery
    • Choose a delivery every 3 to 10 weeks
    • Manage your subscription from your account
    • Free shipping on orders over $75
    • Secure checkout

    Build your routine

    Combine formulas for jaw, scalp, body and face. Orders over $75 ship free.

    Build your routine

    How NX35™ works

    NX35™ is a plant-based biomimetic exosome technology designed to support communication to cells at the molecular level.

    1. 1

      Plant-derived exosomes

      Exosomes are like tiny drones that carry signals directly to your skin cells.

    2. 2

      Cell-to-cell communication

      Using NX35™ technology, they go deep into the skin to support real, lasting change.

    3. 3

      One formula per concern

      Each serum pairs NX35™ with targeted actives: jaw and neck, scalp, body or face.

    Shop the lab

    Meet the Founders

    Founded by scientists.

    Operated by scientists.

    Real science, without the price tag or injection.

    Real reviews from real BioHackers

    Meet the BioHackers

    Never run out. Save 15% on every refill.

    Results come from using it every day. Auto-refill keeps a fresh bottle arriving before you run out.

    $54.40 $64 Shapeshift, per delivery

    Start my subscription
    • 15% off every order

      Your subscriber price applies to every delivery.

    • Free shipping, always

      Every subscription order ships free.

    • Your schedule

      Deliveries every 3 to 10 weeks. Change it whenever you like.

    • No lock-in

      Skip, reschedule or cancel from your account.

    1. 1

      Choose subscribe

      Pick Subscribe & save and a delivery frequency.

    2. 2

      We ship automatically

      Your next bottle arrives before you run out.

    3. 3

      Stay in control

      Manage everything from your account, anytime.

    Questions, answered

    How long until I see results?

    Use ShapeShift morning and night and judge your results at about 4 weeks. Results build with consistent daily use.

    How do I use ShapeShift?

    Apply to clean, dry skin on your jaw, under-chin and neck, morning and night, before moisturizer. Smooth it on with upward strokes; the Gua Sha helps work it in.

    What is NX35™?

    NX35™ is SickScience's plant-based biomimetic exosome technology, designed to support cell-to-cell communication in the skin.

    Is it vegan and fragrance-free?

    Yes. ShapeShift is vegan and free of fragrance and dyes.

    How does the subscription work?

    Pick a delivery frequency from every 3 to 10 weeks and save 15% on every order, with free shipping. You can change your schedule or cancel from your account.

    Is shipping free?

    Subscription orders and orders over $75 ship free.