- 4.7 / 5 from 814 reviews
- 35,000+ happy customers
- 14 awards incl. Oprah, InStyle & Esquire
- Free shipping on orders over $75
Shop the lab
Subscribe on any serum and save 15% on every delivery.
Meet ShapeShift, our #1 bestseller
The award-winning gel-serum for the jawline and neck, powered by NX35™ exosome technology. One minute, morning and night, for a visibly lifted look in about 4 weeks.
- Shop TODAY Mature Beauty Awards 2025
- Cosmopolitan Holy Grail Beauty Awards 2025
- Best Jawline & Neck Treatment, Real Simple Awards 2024
- Visibly lifts the jawline and under-chin area
- Firms and smooths crepey neck skin
- Vegan, fragrance-free and dye-free
- Free shipping on orders over $75
- Secure checkout
$0 todayOprah Beauty O-Wards 2025 winner
Try DropOff free for 21 days
Our body-sculpting gel-serum, risk-free. Pay only shipping today and decide after you've tried it.
- 1Pay shipping only.$0 for the product today.
- 2Try it for 21 days.Use it morning and night.
- 3Love it or return it.Free returns if it's not for you.
A $52 temporary authorization will be placed on your card for the 21-day trial. You may see this amount as pending on your card statement, but you won’t be charged during the trial. If you keep DropOff, you’ll be charged $52 when the trial ends. Start a free return before then and you won’t be charged.
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Build your routine
Combine formulas for jaw, scalp, body and face. Orders over $75 ship free.
How NX35™ works
NX35™ is a plant-based biomimetic exosome technology designed to support communication to cells at the molecular level.
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Plant-derived exosomes
Exosomes are like tiny drones that carry signals directly to your skin cells.
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Cell-to-cell communication
Using NX35™ technology, they go deep into the skin to support real, lasting change.
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One formula per concern
Each serum pairs NX35™ with targeted actives: jaw and neck, scalp, body or face.
Meet the Founders
Founded by scientists.
Operated by scientists.
Real science, without the price tag or injection.
Real reviews from real BioHackers
Meet the BioHackers
Never run out. Save 15% on every refill.
Results come from using it every day. Auto-refill keeps a fresh bottle arriving before you run out.
$54.40
$64
ShapeShift, per delivery
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15% off every order
Your subscriber price applies to every delivery.
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Free shipping, always
Every subscription order ships free.
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Your schedule
Deliveries every 3 to 10 weeks. Change it whenever you like.
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No lock-in
Skip, reschedule or cancel from your account.
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1
Choose subscribe
Pick Subscribe & save and a delivery frequency.
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2
We ship automatically
Your next bottle arrives before you run out.
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Stay in control
Manage everything from your account, anytime.
Questions, answered
How long until I see results?
Use ShapeShift morning and night and judge your results at about 4 weeks. Results build with consistent daily use.
How do I use ShapeShift?
Apply to clean, dry skin on your jaw, under-chin and neck, morning and night, before moisturizer. Smooth it on with upward strokes; the Gua Sha helps work it in.
What is NX35™?
NX35™ is SickScience's plant-based biomimetic exosome technology, designed to support cell-to-cell communication in the skin.
Is it vegan and fragrance-free?
Yes. ShapeShift is vegan and free of fragrance and dyes.
How does the subscription work?
Pick a delivery frequency from every 3 to 10 weeks and save 15% on every order, with free shipping. You can change your schedule or cancel from your account.
Is shipping free?
Subscription orders and orders over $75 ship free.


