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Biotech skincare that shows in the mirror

NX35™ exosome serums for jawline, hair, body and face. Made by two PhD scientists.

  • 4.7 / 5 from 814 reviews
  • 35,000+ happy customers
  • 14 awards incl. Oprah, InStyle & Esquire
  • Free shipping on orders over $75

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Subscribe on any serum and save 15% on every delivery.

PowerCycle

4.5 (126)

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Awards

    4.7 out of 5 from 575 reviews

    Meet ShapeShift, our #1 bestseller

    The award-winning gel-serum for the jawline and neck, powered by NX35™ exosome technology. One minute, morning and night, for a visibly lifted look in about 4 weeks.

    • Shop TODAY Mature Beauty Awards 2025
    • Cosmopolitan Holy Grail Beauty Awards 2025
    • Best Jawline & Neck Treatment, Real Simple Awards 2024
    • Visibly lifts the jawline and under-chin area
    • Firms and smooths crepey neck skin
    • Vegan, fragrance-free and dye-free
    Choose your set
    How do you want it?
    • Free shipping on every delivery
    • Change, skip or cancel anytime from your account
    • Email reminder before each order ships
    • Free shipping on orders over $75
    • Secure checkout
    DropOff $0 today

    Oprah Beauty O-Wards 2025 winner

    Try DropOff free for 21 days

    Our body-sculpting gel-serum, risk-free. Pay only shipping today and decide after you've tried it.

    1. 1Pay shipping only.$0 for the product today.
    2. 2Try it for 21 days.Use it morning and night.
    3. 3Love it or return it.Free returns if it's not for you.

    A $52 temporary authorization will be placed on your card for the 21-day trial. You may see this amount as pending on your card statement, but you won’t be charged during the trial. If you keep DropOff, you’ll be charged $52 when the trial ends. Start a free return before then and you won’t be charged.

    Build your routine

    Combine formulas for jaw, scalp, body and face. Orders over $75 ship free.

    Build your routine

    How NX35™ works

    NX35™ is a plant-based biomimetic exosome technology designed to support communication to cells at the molecular level.

    1. 1

      Plant-derived exosomes

      Exosomes are like tiny drones that carry signals directly to your skin cells.

    2. 2

      Cell-to-cell communication

      Using NX35™ technology, they go deep into the skin to support real, lasting change.

    3. 3

      One formula per concern

      Each serum pairs NX35™ with targeted actives: jaw and neck, scalp, body or face.

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    Meet the Founders

    Founded by scientists.

    Operated by scientists.

    Real science, without the price tag or injection.

    Real reviews from real BioHackers

    Meet the BioHackers

    Never run out. Save 15% on every refill.

    Results come from using it every day. Auto-refill keeps a fresh bottle arriving before you run out.

    $54.40 $64 ShapeShift, per delivery

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    • 15% off every order

      Your subscriber price applies to every delivery.

    • Free shipping, always

      Every subscription order ships free.

    • Your schedule

      Deliveries every 3 to 10 weeks. Change it whenever you like.

    • No lock-in

      Skip, reschedule or cancel from your account.

    1. 1

      Choose subscribe

      Pick Subscribe & save and a delivery frequency.

    2. 2

      We ship automatically

      Your next bottle arrives before you run out.

    3. 3

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      Manage everything from your account, anytime.

    Questions, answered

    How long until I see results?

    Use ShapeShift morning and night and judge your results at about 4 weeks. Results build with consistent daily use.

    How do I use ShapeShift?

    Apply to clean, dry skin on your jaw, under-chin and neck, morning and night, before moisturizer. Smooth it on with upward strokes; the Gua Sha helps work it in.

    What is NX35™?

    NX35™ is SickScience's plant-based biomimetic exosome technology, designed to support cell-to-cell communication in the skin.

    Is it vegan and fragrance-free?

    Yes. ShapeShift is vegan and free of fragrance and dyes.

    How does the subscription work?

    Pick a delivery frequency from every 3 to 10 weeks and save 15% on every order, with free shipping. You can change your schedule or cancel from your account.

    Is shipping free?

    Subscription orders and orders over $75 ship free.